Thyroid Function

Understanding Thyroid Function: A Functional Medicine Approach to Hormonal Health

Authored by Chris McDermott, APRN, practicing with autonomous authority in Florida

Introduction

The thyroid gland is a small, butterfly-shaped organ at the base of the neck, yet it exerts a wide influence over metabolism, energy production, temperature regulation, and hormonal balance. When thyroid hormones are out of sync—too high, too low, or improperly converted—multiple systems throughout the body can be disrupted.
At Intercoastal Health, our functional medicine practitioner evaluates the full spectrum of thyroid function, identifying imbalances early, uncovering root causes, and implementing lifestyle-based and biomarker-driven strategies to restore optimal thyroid health.

What Is Thyroid Dysfunction?

Thyroid dysfunction encompasses any abnormality in how the thyroid produces and regulates hormones. Key conditions include:

Each disruption carries unique risks, but all can profoundly affect energy, mood, and overall well-being.

Key Thyroid Hormones and Their Roles

Understanding thyroid health begins with the hormones themselves:

  • Thyroxine (T4): The primary, largely inactive hormone secreted by the thyroid.
  • Triiodothyronine (T3): The active form that binds to cellular receptors to regulate metabolism.
  • Thyroid-Stimulating Hormone (TSH): Released by the pituitary, it directs the thyroid to produce T4 and T3.
  • Reverse T3 (rT3): An inactive isomer that may rise in stress, blocking T3 receptors.

A comprehensive functional panel measures not only TSH, but also Free T4, Free T3, rT3, and thyroid antibodies to reveal subtle imbalances.

Recognizing Symptoms of Thyroid Imbalance

Hypothyroid Symptoms

  • Fatigue and sluggishness
  • Weight gain or difficulty losing weight
  • Cold intolerance
  • Constipation
  • Depression or mood disturbances
  • Dry skin and brittle nails
  • Hair thinning (including outer brows)
  • Slow heart rate
  • Puffiness around the eyes

Hyperthyroid Symptoms

  • Anxiety, restlessness
  • Unintentional weight loss
  • Heat intolerance and sweating
  • Rapid heartbeat or palpitations
  • Tremors and muscle weakness
  • Insomnia
  • Frequent bowel movements
  • Goiter or gland enlargement

Thyroiditis & Nodules

  • Transient hyper- followed by hypothyroid phases
  • Neck pain or tenderness
  • Difficulty swallowing or hoarseness in large nodules

Functional Medicine Evaluation of Thyroid Health

Rather than relying solely on TSH, we assess a full thyroid panel to capture conversion dynamics, immune status, and receptor sensitivity:

Biomarker

Purpose

TSH

Pituitary signaling

Free T4

Inactive hormone availability

Free T3

Active hormone for tissue use

Reverse T3

Inactive form that blocks T3 action

TPO Antibodies

Autoimmune marker for Hashimoto’s

Tg Antibodies (TgAb)

Additional autoimmunity screening

We may also order imaging (thyroid ultrasound or fine-needle biopsy) when nodules or structural changes are suspected.

Root Causes of Thyroid Dysfunction

A functional medicine approach digs into upstream contributors rather than simply treating downstream symptoms:

  1. Autoimmunity
    • Hashimoto’s and Graves’ disease disrupt normal hormone production.
  2. Iodine Imbalance
    • Both deficiency (goiter risk) and excess (triggering dysfunction) can occur.
  3. Environmental Toxins
    • BPA, phthalates, heavy metals impede hormone pathways.
  4. Chronic Stress & Adrenal Strain
    • Elevated cortisol alters conversion and receptor sensitivity.
  5. Nutrient Deficiencies
    • Selenium, zinc, iron, vitamin D, and tyrosine are critical cofactors.
  6. Gut & Liver Health
    • Inflammation, dysbiosis, or hepatic impairment hinders hormone conversion and clearance.

Functional Medicine Treatment Strategy

1. Targeted Nutrition

  • Anti-inflammatory whole-food diet rich in leafy greens, wild-caught fish, and healthy fats.
  • Gluten and dairy elimination for autoimmune cases.
  • Supplementation with selenium (200 mcg/day), zinc, iron, vitamin D, and tyrosine as indicated.

2. Hormonal Axis Support

  • Adaptogens (ashwagandha, rhodiola) to balance the hypothalamic-pituitary-thyroid axis.
  • Assess and support adrenal health to improve T4→T3 conversion.

3. Medication Management

  • Hypothyroid: Levothyroxine (T4), liothyronine (T3), or natural desiccated thyroid.
  • Hyperthyroid: Antithyroid agents, beta-blockers, or referral for radioiodine/surgery.
  • Dosing is individualized, with ongoing lab monitoring and symptom tracking.

4. Detoxification & Gut Repair

  • Support liver detox pathways (milk thistle, N-acetylcysteine) to optimize conversion.
  • Heal gut integrity (probiotics, glutamine, avoidance of inflammatory foods).

5. Lifestyle Optimization

  • Stress reduction (mindfulness, yoga, breathwork) to lower cortisol.
  • Regular exercise tailored to energy levels.
  • Sleep hygiene to regulate hormone rhythms.

Monitoring and Preventing Complications

Regular retesting every 8–12 weeks ensures that interventions are effective and safe. Untreated thyroid dysfunction can lead to:

  • Cardiovascular Disease: Arrhythmias, high cholesterol, hypertension
  • Bone Loss: Osteoporosis risk with hypo- or hyperthyroidism
  • Mental Health: Anxiety, depression, cognitive decline
  • Reproductive Issues: Infertility, menstrual irregularities
  • Life-Threatening Crises: Myxedema coma or thyroid storm

Further Reading

In conclusion, a comprehensive evaluation by a functional medicine nurse practitioner in Florida facilitates identification of cellular-level and molecular imbalances driving thyroid disorders. By integrating evidence-based therapies with IV Therapy and Regenerative Medicine services—where hormone optimization and tissue support are paramount—we offer patients a regenerative, preventive framework to rebuild metabolic resilience and optimize wellness. Call (904) 799-2531 or schedule online to request your personalized thyroid health assessment.

Board Certified & Professional Member of

American Academy of Nurse Practitioners
Florida Association of Nurse Practitioner
The American Association of Nurse Practitioners
American Academy of Anti-Aging Medicine
International Association of Rehabilitation Professionals

Schedule your visit today!

Ready to take the next step in optimizing your health? Contact us to schedule a comprehensive functional medicine evaluation centered on whole-person care. We offer convenient in-person and telemedicine appointments. Our team is available to assist with scheduling and to ensure you receive the support and care you need.

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